No huge differences, just some new (and neat) equipment.
First you'd wanna check out getting a
Qiqirn Sash/+1 by level 40. They're probably the best thing you can wear till you get a Heirarch belt at 71.
Second is the slightly more expensive
Beak Necklace at 50, which is also tremendously useful.
As far as gameplay mechanics themselves, nothing has really changed pre-50. Just cure your PT up, make sure people don't die, and enjoy yourself
